Hormones and neoplasia

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Hormones and neoplasia.

A phenomenon, the explanation of which still eludes us, is the regression of human breast cancer which may follow alterations in the hormonal environment. It was first observed in 1895 when recurrent cancer of the breast in a 33-year-old Glasgow woman remitted following removal of the ovaries (Beatson, 1896). The therapeutic advances which followed this observation are well known and include th...

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Sex hormones and hepatic neoplasia.

The recent increase in hepatocellular neoplasms in women of child-bearing age taking oral contraceptives and in individuals of both sexes taking anabolic androgenic steroids is a phenomenon that requires urgent attention. Although most of the lesions are benign, reports of carcinomas in a few of these individuals and our own observation of an adenoma that shows borderline malignant transformati...

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Hormones and Sexual Disordors

The Paper is divided into two parts; at first: The role of endocrine system on anatomical development of internal and external sexual organs; Second part discusses the Endocrine View point of gender identity gender role, impotence, frigidity and other psychosexual disorders like homosexualism and transsexualism. 

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Chromogranin A as serum marker for neuroendocrine neoplasia: comparison with neuron-specific enolase and the alpha-subunit of glycoprotein hormones.

Chromogranin A (CgA) is gaining acceptance as a serum marker of neuroendocrine tumors. Its specificity in differentiating between neuroendocrine and nonneuroendocrine tumors, its sensitivity to detect small tumors, and its clinical value, compared with other neuroendocrine markers, have not clearly been defined, however. The objectives of this study were to evaluate the clinical usefulness of C...

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Efficacy of combination therapy of Methotrexate and Vitamin A in low risk gestational trophoblastic neoplasia treatment

Introduction: Methotrexate as a single agent chemotherapy in most women with low risk gestational trophoblastic neoplasia (GTN) has been associated with high treatment rate. Combination of methotrexate with Vitamin A due to reduced number of chemotherapy regime courses is one of the treatment options for patients with low-risk GTN. Therefore, this study was performed with aim to determine the e...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1974

ISSN: 0021-9746

DOI: 10.1136/jcp.s3-7.1.65